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Head of Supply Chain

Department: CMC Platform
Location: Durham, NC

Job Summary

The Head of Supply Chain will be a key member of the CMC Technical Operations team which aims to drive operational excellence for the successful development Precision Biosciences’ Cell and Gene Therapy Products, including allogeneic CAR-T cells, AAV viral vectors, and Lipid Nanoparticle-Encapsulated mRNA.

The Head of Supply Chain will conceptualize and implement supply chain processes to support clinical programs and in preparation for licensure and large-scale distribution. The individual will manage sourcing, inventory, and disposition of critical starting material, intermediates, drug substances and drug products. The Head of Supply Chain will work in closely with clinical operations and product development leaders to ensure timely distribution of investigational drug products to clinical sites. The individual will also work closely with the Head of Manufacturing to define and implement the optimal flow of raw materials through finished goods at Precision’s new GMP manufacturing facility. He/she will contribute to the continuous optimization of Supply Chain Management tools for multiple platforms and products and throughout the entire product development life-cycle through to BLA. The ideal candidate will have a proven track record in conceptualizing and implementing Supply Chain Management “Plan, Source, Make, Deliver” functions in a fast-paced novel therapeutics environment, with extensive experience managing third party supplier networks with a focus on quality, reliability, sustainability, speed, and cost. Skills in operational risk analysis, financial and operational modeling, and decision analysis are highly advantageous.

Essential Duties and Responsibilities

Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of this position. This list contains the major duties and requirements of the job and is not all-inclusive. Incumbent(s) may be expected to perform role-related duties other than those contained in this document.

Build and implement Precision Biosciences’ supply chain management function including ultra-cold chain logistics to support multiple early phase cell and gene therapy clinical programs through to commercial launch

Manage and coordinate sourcing and supply for internal or outsourced activities to ensure timely procurement and distribution of material

Develop, implement and continuously refine forecasting and inventory management tools to ensure timely and cost-effective product procurement. Set supply chain metrics and goals

Lead cross-functional interactions with key stakeholders (e.g. Development Program Leads, Clinical, Manufacturing, Quality, Finance) to support product life-cycle needs

Identify, vet, and manage a complex network of third party vendors including contract negotiations, establishing supply agreements, and audits and quality agreements in partnership with Quality Assurance


The requirements listed below are representative of the knowledge, skill, and/or ability required to perform this job successfully.


Work Environment

The work environment characteristics described here are representative of those an employee could potentially encounter while performing the essential functions of this job.

Physical Demands

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Travel Requirements

Precision BioSciences’ mission and vision is to translate the world’s most powerful genome editing technology into greatly needed products throughout the life sciences, by being the conduit through which the greatest genome engineering challenges are solved. Precision’s wholly proprietary ARCUS genome editing platform enables the production of highly specific nucleases that can insert, remove, and modify DNA at essentially any location in a complex genome. Through our ARCUS platform, we are developing genome editing-based products to address critical needs in oncology, genetic disease, agriculture, and beyond. For additional information, please visit

Precision BioSciences provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, disability, genetic information, marital status, amnesty, or status as a covered veteran in accordance with applicable federal, state and local laws. Precision BioSciences complies with applicable state and local laws governing non-discrimination in employment in every location in which the company has facilities. This policy applies to all terms and conditions of employment, including, but not limited to, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.

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